Home Non-Invasive Ventilation Use Following Acute Hypercapnic Respiratory Failure in Chronic Obstructive Pulmonary Disease

Publication: Respiratory Medicine

Study Authors: Matos, P; Kampelmacher, MJ; Esquinas, AM

Publisher: Science Direct

In 2011, 166 COPD patients were studied to evaluate the effectiveness of Non-Invasive Positive Pressure Ventilation (NPPV). Half of the patients utilized the at-home therapy; the other half did not. Over the course of 6 months, these were the findings.

“Results: Patients in the NPPV post discharge group demonstrated superior event-free survival compared to the no-NPPV post discharge group (х2 = 23.8, p < 0.0001). The NPPV post discharge group had a statistically significant reduction in hospital readmissions (40% versus 75%, p < 0.0001) through 180 days from the index admission.

Conclusions: Patients who used NPPV following an admission for AECOPD with hypercapnic respiratory failure had lower readmission rates and improved event-free survival after 180 days from an index admission compared to patients who did not use NPPV post discharge.”

Full text: https://www.sciencedirect.com/science/article/pii/S0954611114001140

“Home non-invasive ventilation use following acute hypercapnic respiratory failure in COPD”; Respiratory Medicine, COPYRIGHT 2011.